GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs7611238 | 1 | rs823311 | chr3:195141029 | C3orf21 | chr3:194789015-194991895:- | -0.28 | -5.38 | 1.28E-7 | Body mass index |
| BLCA | cis | rs7611238 | 1 | rs823314 | chr3:195132402 | C3orf21 | chr3:194789015-194991895:- | -0.29 | -5.54 | 5.62E-8 | Body mass index |
| BLCA | cis | rs12220238 | 1 | rs8255 | chr10:75879750 | ADK | chr10:75910965-76469059:+ | 0.28 | 4.33 | 1.89E-5 | Soluble interleukin-2 receptor subunit alpha |
| BLCA | cis | rs10461617 | 1 | rs832551 | chr5:56180112 | C5orf35 | chr5:56205103-56213010:+ | 0.75 | 11.53 | 1.32E-26 | Type 2 diabetes |
| BLCA | cis | rs10461617 | 1 | rs832553 | chr5:56114786 | C5orf35 | chr5:56205103-56213010:+ | 0.73 | 11.16 | 3.06E-25 | Type 2 diabetes |
| BLCA | cis | rs10461617 | 1 | rs832554 | chr5:56115036 | C5orf35 | chr5:56205103-56213010:+ | 0.71 | 10.97 | 1.51E-24 | Type 2 diabetes |
| BLCA | cis | rs10461617 | 1 | rs832565 | chr5:56150803 | C5orf35 | chr5:56205103-56213010:+ | 0.75 | 11.66 | 4.12E-27 | Type 2 diabetes |
| BLCA | cis | rs10461617 | 1 | rs832568 | chr5:56153776 | C5orf35 | chr5:56205103-56213010:+ | 0.74 | 11.25 | 1.5E-25 | Type 2 diabetes |
| BLCA | cis | rs10461617 | 1 | rs832569 | chr5:56154584 | C5orf35 | chr5:56205103-56213010:+ | 0.74 | 11.25 | 1.5E-25 | Type 2 diabetes |
| BLCA | cis | rs10461617 | 1 | rs832578 | chr5:56164223 | C5orf35 | chr5:56205103-56213010:+ | 0.74 | 11.69 | 3.42E-27 | Type 2 diabetes |
| BLCA | cis | rs10461617 | 1 | rs832582 | chr5:56177743 | C5orf35 | chr5:56205103-56213010:+ | 0.74 | 11.45 | 2.62E-26 | Type 2 diabetes |
| BLCA | cis | rs10461617 | 1 | rs832583 | chr5:56178217 | C5orf35 | chr5:56205103-56213010:+ | 0.74 | 11.45 | 2.62E-26 | Type 2 diabetes |
| BLCA | cis | rs10461617 | 1 | rs832584 | chr5:56179212 | C5orf35 | chr5:56205103-56213010:+ | -0.73 | -11.03 | 9.55E-25 | Type 2 diabetes |
| BLCA | cis | rs853679 | 1 | rs853678 | chr6:28297313 | ZNF389 | chr6:28129551-28137375:+ | -0.31 | -3.89 | 0.000117 | Depression |
| BLCA | cis | rs853679 | 1 | rs853679 | chr6:28296863 | ZNF389 | chr6:28129551-28137375:+ | -0.31 | -3.89 | 0.000117 | Depression |